Bioelectronics at the Single Molecule Level

Gul O. T., Pugliese K. M., Choi Y., Rajapakse A. J., Lau C. J., Kumar N., ...More

64th Annual IEEE International Electron Devices Meeting, IEDM 2018, California, United States Of America, 1 - 05 December 2018, vol.2018-December, (Full Text) identifier

  • Publication Type: Conference Paper / Full Text
  • Volume: 2018-December
  • Doi Number: 10.1109/iedm.2018.8614591
  • City: California
  • Country: United States Of America
  • Ankara Haci Bayram Veli University Affiliated: Yes

Abstract

© 2018 IEEE.Bioelectronic devices built with single molecules of a protein, enzyme, or aptamer represent a new class of hybrid electronics. When biofunctionalization of nanoscale conductors is reduced to one molecule, that molecule's dynamic activity can be transduced into a large amplitude, high bandwidth electronic output. Using DNA polymerase I as an example, we show that single-molecule bioelectronics reveal biochemical activity with bond-by-bond resolution.