©, Copyright Association of Energy Engineers (AEE).This study empirically observed the nexus between nuclear energy consumption and economic growth in the country of Spain. Unit root and stationarity tests, Johansen cointegration tests, vector error correction models (VECM), and Granger causality tests were applied to annual data for the years 1968 to 2014. Empirical results confirmed the existence of a long-term equilibrium relationship between two variables and showed that nuclear energy consumption using Granger causality tests causes economic growth, which leads to important policy implications. Spain is an oil-importing country. As environmental concerns increase, policy makers should consider increasing the share of nuclear power in the country's energy portfolio since it provides energy with no carbon emissions. However, policy makers should consider the safety measures and the correct disposal methodologies for nuclear waste.