Magnetic Phase-Change Nanodroplets for Magnetic Particle Imaging and Magnetic Vaporization
International Journal on Magnetic Particle Imaging, cilt.11, 2025 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 11
- Basım Tarihi: 2025
- Doi Numarası: 10.18416/ijmpi.2025.2503002
- Dergi Adı: International Journal on Magnetic Particle Imaging
- Derginin Tarandığı İndeksler: Scopus
- Ankara Hacı Bayram Veli Üniversitesi Adresli: Hayır
Özet
Phase-change nanodroplets (PCNs) are high-potent theranostic agents for efficient and targeted drug delivery. PCNs can be functionalized to accumulate in tumors and vaporized by external stimuli. Ultrasound (US) is the primary method for PCN vaporization and imaging. However, it has limitations due to wave propagation effects, a relatively high vaporization pressure, and a low scattering cross section of PCNs in the liquid phase. Here, we report magnetic phase-change nanodroplets (MPCNs) suitable for magnetic particle imaging (MPI) and vaporization with magnetic heating. MPCNs can enable quantitative monitoring of accumulation in the disease site using MPI, and vaporization with targeted magnetic heating, thereby improving the clinical potential of PCNs as a theranostic agent.