Nanoporous polymeric nanofibers based on selectively etched PS- b -PDMS block copolymers

Demirel G., BÜYÜKSERİN F., Morris M. A., DEMİREL G.

ACS Applied Materials and Interfaces, vol.4, no.1, pp.280-285, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1021/am201331b
  • Journal Name: ACS Applied Materials and Interfaces
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.280-285
  • Keywords: block copolymer self-assembly, anodic alumina membrane, nanoporous materials, ultrasound triggered drug delivery, DRUG-DELIVERY, THIN-FILMS, TEMPERATURE, CAVITATION, TEMPLATES
  • Ankara Haci Bayram Veli University Affiliated: No

Abstract

One-dimensional nanoporous polymeric nanofibers have been fabricated within an anodic aluminum oxide (AAO) membrane by a facile approach based on selective etching of poly(dimethylsiloxane) (PDMS) domains in polystyrene-block- poly(dimethylsiloxane) (PS-b-PDMS) block copolymers that had been formed within the AAO template. It was observed that prior to etching, the well-ordered PS-b-PDMS nanofibers are solid and do not have any porosity. The postetched PS nanofibers, on the other hand, had a highly porous structure having about 20-50 nm pore size. The nanoporous polymeric fibers were also employed as a drug carrier for the native, continuous, and pulsatile drug release using Rhodamine B (RB) as a model drug. These studies showed that enhanced drug release and tunable drug dosage can be achieved by using ultrasound irradiation. © 2011 American Chemical Society.