Bioelectronics at the Single Molecule Level

Gul O. T., Pugliese K. M., Choi Y., Rajapakse A. J., Lau C. J., Kumar N., ...Daha Fazla

64th Annual IEEE International Electron Devices Meeting, IEDM 2018, California, Amerika Birleşik Devletleri, 1 - 05 Aralık 2018, cilt.2018-December identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası: 2018-December
  • Doi Numarası: 10.1109/iedm.2018.8614591
  • Basıldığı Şehir: California
  • Basıldığı Ülke: Amerika Birleşik Devletleri
  • Ankara Hacı Bayram Veli Üniversitesi Adresli: Evet

Özet

© 2018 IEEE.Bioelectronic devices built with single molecules of a protein, enzyme, or aptamer represent a new class of hybrid electronics. When biofunctionalization of nanoscale conductors is reduced to one molecule, that molecule's dynamic activity can be transduced into a large amplitude, high bandwidth electronic output. Using DNA polymerase I as an example, we show that single-molecule bioelectronics reveal biochemical activity with bond-by-bond resolution.