Doping agent naphazoline hydrochloride: Development of simple and fast voltammetric method for its determination in human serum
Journal of the Turkish Chemical Society, Section A: Chemistry, cilt.6, sa.1, ss.79-88, 2019 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 6 Sayı: 1
- Basım Tarihi: 2019
- Doi Numarası: 10.18596/jotcsa.450793
- Dergi Adı: Journal of the Turkish Chemical Society, Section A: Chemistry
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.79-88
- Anahtar Kelimeler: Aluminum oxide nanoparticles, Doping agent, Electrochemical techniques, Human serum, Naphazoline
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ankara Hacı Bayram Veli Üniversitesi Adresli: Evet
Özet
© 2019, Turkish Chemical Society. All rights reserved.Electrochemical behavior of naphazoline hydrochloride on a carbon paste electrode that was modified with aluminium oxide nanoparticles (Al2O3NPs) was investigated in a Britton-Robinson (BR) buffer (pH 7.0) using various voltammetric techniques. The results support the presence of an irreversible and diffusion-controlled electrochemical oxidation signal of naphazoline hydrochloride which is approximately at 0.9 V vs. Ag/AgCl. A selective, accurate, and simple square-wave anodic adsorptive stripping voltammetric method was proposed for naphazoline hydrochloride detection. The linear response was within the range of 5.0 × 10-8-3.0 × 10-5 mol L-1 with a detection limit of 2.6 × 10-9 mol L-1 (0.642 μg L-1). In addition, the proposed method was also utilized for naphazoline hydrochloride determination in human serum sample.